Dr. Shailini Singh

Dr. Shailini Singh |Clyto Access

Director of Metabolic syndrome Center at NYU Langone Medical Center, USA

Keynote Speaker

Expertise: Perinatal medicine, obesity, hypertension and diabetes

Biography:

Dr. Shailini Singh was born and raised in India. After earning her undergraduate degree from Banaras Hindu University and her medical degree from the Medical School at Lady Hardinge Medical College, New Delhi, India, she proceeded to Canada in January 1968 to become an Obstetrician and Gynecologist. She received her FRCS(C) from there and moved to USA in 1975. She became the first Maternal Fetal Medicine fellow at Harvard Medical School and Joslin Diabetes Foundation in 1975. There she had the privilege to work with Dr. Priscilla White, who was the God mother to all pregnant diabetic patients.Dr. Singh did her second fellowship from the University of Colorado. Following which she stayed on for next 10 years as a faculty in the obstetrician / gynecology department at the University. In 1993-1994 she was a senior Fulbright Scholar to AIIMS, New Delhi India. During her tenure as a Fulbright Scholar she taught around the country as well as conducted research on the effects of Chronic Maternal Anemia on fetus at AIIMS, and Safdarjang Hospital, New Delhi.Currently she is a director of Metabolic syndrome Center at NYU Langone Medical Center, USA. She also had some training in invasive prenatal diagnosis from University of Puericulture in Paris, France and also worked at King Faisal Medical Center in Riyadh, Saudi Arabia through Yale Medical School Saudi- US project.

Presentation:

Title: Metabolic Syndrome (MS): Perils of pregnancy and precursor of childhood obesity and future development of MS

Abstract:

Pregnancy associated with maternal MS is a challenge to manage. Metabolic Syndrome comprises of visceral and/or truncal obesity, hyperlipidemia, hypertension, coronary artery disease (CAD) and Insulin resistance(IR). Insulin resistance can present itself with varied severity as impaired fasting glucose(IFG), Impaired glucose tolerance (IGT), gestational diabetes (GDM) and finally developing overt Type 2 diabetes mellitus (T2DM). In 2008 global Summit IDF president declared “ there is global Pandemic of diabetes mellitus in the new millennium that is a threat to cardiovascular health and world economy”. He gave some stunning statistics that in 2025 without any intervention it’s predicted that there will be 800 million T2DM,that is 15% of the world population.There are ethnic variations in diabetes in women. Compared to western population, Asians develop diabetes at younger ages, at lower degree of obesity and at much higher rates, given the same amount of weight gain. Asians have less muscle mass that leads to increased propensity for insulin resistance compared to western population. This “ metabolically obese” phenotype among normal weight individuals may explain the increased predisposition for diabetes despite relatively low prevalence of truncal obesity. We have data that indicates that Asians have beta cell defect. The pre-pregnancy maternal obesity is an independent risk factor than weight gains during pregnancy. The larger the weights gain higher the birth weight (BW). Maternal obesity is also associated with gestational hypertension and pre eclampsia, also IGT, GDM leading to shoulder dystocia and cesarean delivery. In the offspring it increased the risk of congenital malformation. HAPO trial showed that maternal blood sugars below the cut offs for GDM still increases perinatal morbidity and childhood obesity. Management of these requires a team approach and will be discussed.

Related Conferences :

International Diabetes and Degenerative Diseases Conference